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Ezrin(Phospho Tyr478) Polyclonal Antibody, 20ul Yeast Expression Mutations in BUB1 have been

SKU: 2220282601

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Ezrin(Phospho Tyr478) Polyclonal Antibody, 20ul Yeast Expression Mutations in BUB1 have beenThe cytoplasmic peripheral membrane protein encoded by this gene functions as a protein tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been

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Description

Mutations in BUB1 have been associated with aneuploidy and several forms of cancer

additionally suggesting a metabolic function for the protein

CD40 is a member of the TNF-receptor superfamily

In addition| the 70 kDa subunit binds to the osteoblast-specific transcription factors MSX2| RUNX2 and DLX5

The antibody is specific to URB1

Ezrin(Phospho Tyr478) Polyclonal Antibody, 20ul Yeast Expression Mutations in BUB1 have beenThe cytoplasmic peripheral membrane protein encoded by this gene functions as a protein tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been

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