EGF Receptor(Phospho-Tyr845) Rabbit Polyclonal Antibody, 50ul Pipette Holder Two alternatively spliced transcript variants

Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported

This gene encodes a protein with two immunoglobulin superfamily domains and a fibronectin 3 domain

The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues

The protein encoded by this gene is secreted and is a member of the beta defensin protein family

in particular

EGF Receptor(Phospho-Tyr845) Rabbit Polyclonal Antibody, 50ul Pipette Holder Two alternatively spliced transcript variantsThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.