TRAIP Rabbit Polyclonal Antibody, 50ul Protein Research BMP6 (bone morphogenetic protein 6)

BMP6 (bone morphogenetic protein 6) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

Defects in this gene are a cause of macular corneal dystrophy (MCD)

MIM 603072)

397 amino acid coiled-coil protein

This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases

TRAIP Rabbit Polyclonal Antibody, 50ul Protein Research BMP6 (bone morphogenetic protein 6)This gene encodes a protein that contains an N terminal RING finger motif and a putative coiled coil domain. A similar murine protein interacts with TNFR associated factor 1 (TRAF1) TNFR associated factor 2 (TRAF2) and cylindromatosis. The interaction with TRAF2 inhibits TRAF2 mediated nuclear factor kappa B subunit 1 activation that is required for cell activation and protection against apoptosis.