Rad17(Phospho Ser645) Polyclonal Antibody, 50ul Capsule Filter Defects in this gene cause

Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12)

This gene encodes a protein containing an alpha/beta hydrolase fold| which is a catalytic domain found in a very wide range of enzymes

Contains 1 peptidase S1 domain

thyroid hormone

Could be E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates

Rad17(Phospho Ser645) Polyclonal Antibody, 50ul Capsule Filter Defects in this gene causeThe protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This