p53 Polyclonal Antibody, 50ul[BT-AP06832] Molecular Sciences The DNA damage induced chromatin

The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM

T-cell acute lymphoblastic leukemia

UBCE7IP1 isoform 3 (ZIN)

This kinase contains multiple functional domains

Numerous pseudogenes have been reported for this gene

p53 Polyclonal Antibody, 50ul[BT-AP06832] Molecular Sciences The DNA damage induced chromatinTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni