Sclerostin Polyclonal Antibody, 50ul sgRNA Library Construction Transcript variants encoding different isoforms
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Sclerostin Polyclonal Antibody, 50ul sgRNA Library Construction Transcript variants encoding different isoformsSclerostin (SOST) is a secreted glycoprotein with a C terminal cysteine knot like (CTCK) domain and sequence similarity to the DAN (differential screening selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss of function mutations in SOST are associated with an autosomal recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of SOST, which causes reduced
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