IKK gamma Polyclonal Antibody, 100ul[BT-AP02164] Cell Function Analysis 60 ℃ (HB60-S)

60 ℃ (HB60-S)

The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1| MAPKK4) in vitro| and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells

It was also found to be expressed in several cancer cell lines| but not in the corresponding normal tissues

or processing transcripts

It also may be involved in the assembly of the B

IKK gamma Polyclonal Antibody, 100ul[BT-AP02164] Cell Function Analysis 60 ℃ (HB60-S)This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.