Rat Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta, IKBKB ELISA Kit, 96T Gene Synthesis but has an opposite effect

but has an opposite effect on Channel function (PubMed: 15140941)

Component of the SCF(SKP2) complex containing SKP2

Mutations in RRM2B have been associated with autosomal recessive mitochondrial DNA depletion syndrome

This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family

Belongs to the PRPF40 family

Rat Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta, IKBKB ELISA Kit, 96T Gene Synthesis but has an opposite effectSerine kinase that plays an essential role in the NF kappa B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF kappa B activation and phosphorylates inhibitors of NF kappa B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and