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RFWD3 Polyclonal Antibody, 100ul DNA Fragments This gene encodes a member

SKU: 26842064147

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RFWD3 Polyclonal Antibody, 100ul DNA Fragments This gene encodes a memberRFWD3, also named as RNF201, is a E3 ubiquitin protein ligase that mediates the ubiquitination of p53 TP53 in the late response to DNA damage, and acts as a positive regulator of p53 TP53 stability, thereby regulating the G1 S DNA damage checkpoint. RFWD3 may act by catalyzing the formation of short polyubiquitin chains on p53 TP53 that are not targeted to the proteasome. In response to ionizing radiation, It interacts with MDM2 and enhances p53 TP53

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Description

This gene encodes a member of the neurexin protein family

GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane

regulatory peptides of the brain and gastrointestinal tract

ADGRB2 (adhesion G protein-coupled receptor B2) encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family

In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts

RFWD3 Polyclonal Antibody, 100ul DNA Fragments This gene encodes a memberRFWD3, also named as RNF201, is a E3 ubiquitin protein ligase that mediates the ubiquitination of p53 TP53 in the late response to DNA damage, and acts as a positive regulator of p53 TP53 stability, thereby regulating the G1 S DNA damage checkpoint. RFWD3 may act by catalyzing the formation of short polyubiquitin chains on p53 TP53 that are not targeted to the proteasome. In response to ionizing radiation, It interacts with MDM2 and enhances p53 TP53

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