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CBX2 Polyclonal Antibody, 100ul Cellular Function Assays The exact function of Staufen

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CBX2 Polyclonal Antibody, 100ul Cellular Function Assays The exact function of StaufenCBX2 (chromobox 2) encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of CBX2 in mice results in male to female gonadal sex reversal. Mutations in CBX2 are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms

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Description

The exact function of Staufen homolog 2 is not known| but since it contains 3 copies of conserved dsRNA binding domain| it could be involved in double-stranded RNA binding events

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Proapoptotic activity of BCL2 associated agonist of cell death is regulated through its phosphorylation

This gene encodes a protein initially identified as a thyroid-specific transcription factor

CBX2 Polyclonal Antibody, 100ul Cellular Function Assays The exact function of StaufenCBX2 (chromobox 2) encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of CBX2 in mice results in male to female gonadal sex reversal. Mutations in CBX2 are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms

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