Caspase 2 Rabbit Polyclonal Antibody, 50ul[BT-AP06905] Nucleic Acid Isolation & Purification GRK5 encodes a member of

GRK5 encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family

Two transcript variants encoding two different isoforms have been found for APOL4

Contains 2 TSP type-1 domains

|Contains 2 phorbol-ester/DAG-type zinc fingers

|PTM:Phosphorylated by CIT (Rho-associated kinase) (By similarity)

Caspase 2 Rabbit Polyclonal Antibody, 50ul[BT-AP06905] Nucleic Acid Isolation & Purification GRK5 encodes a member ofalternative products: Isoforms differ in the N and C termini Catalytic activity: Strict requirement for an Asp residue at P1 with 316 asp being essential for proteolytic activity and has a preferred cleavage sequence of Val Asp Val Ala Asp . Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.