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Cyclin B1(Phospho Ser147) Polyclonal Antibody, 100ul Antibody Humanization APC encodes a tumor suppressor

SKU: 2796188243

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DKK141.00 DKK181.00

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Cyclin B1(Phospho Ser147) Polyclonal Antibody, 100ul Antibody Humanization APC encodes a tumor suppressorThe protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle regulated transcript, that is expressed predominantly during G2 M phase. The different transcripts result from the use of alternate transcription initiation sites.

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Description

APC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway

Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome

The proteins of this family are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues

Microtubule affinity regulating kinase 3 encoded by MARK3 is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4

granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells

Cyclin B1(Phospho Ser147) Polyclonal Antibody, 100ul Antibody Humanization APC encodes a tumor suppressorThe protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle regulated transcript, that is expressed predominantly during G2 M phase. The different transcripts result from the use of alternate transcription initiation sites.

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