AATC Polyclonal Antibody, 20ul[BT-AP05896] Funnels All 3 proteins bind with

All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner

POLD3 encodes the 66-kDa subunit of DNA polymerase delta

down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex

The subunit encoded by NDUFS6 is one of seven subunits in the iron-sulfur protein fraction

It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix

AATC Polyclonal Antibody, 20ul[BT-AP05896] Funnels All 3 proteins bind withGlutamic oxaloacetic transaminase is a pyridoxal phosphate dependent enzyme which exists in cytoplasmic and mitochondrial forms GOT1 and GOT2 respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.