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c-Fms(Phospho Tyr561) Polyclonal Antibody, 50ul Molecular Biology Chromosomal translocations involving this gene

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c-Fms(Phospho Tyr561) Polyclonal Antibody, 50ul Molecular Biology Chromosomal translocations involving this geneThe protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1 PDGF

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Description

Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia

Implicated in endocytosis

PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes

which catalyzes the removal of the 3' trailer from precursor tRNAs

CUL2 not CUL3

c-Fms(Phospho Tyr561) Polyclonal Antibody, 50ul Molecular Biology Chromosomal translocations involving this geneThe protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1 PDGF

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