Haptoglobin Polyclonal Antibody, 50ul[BT-AP09816] Cell Separation and Collection MIM 603850)

MIM 603850)

Three transcript variants encoding two different proteins have been found for this gene

Fbls containing leucine-rich repeats

This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL)

The encoded protein is secreted and binds hydroxyapatite with high affinity

Haptoglobin Polyclonal Antibody, 50ul[BT-AP09816] Cell Separation and Collection MIM 603850)This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and or its regulatory regions