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PDHK1(Phospho Tyr243) Rabbit Polyclonal Antibody, 100ul[BT-AP11860] DNA Libraries Synthesis Polymorphisms in this gene have

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PDHK1(Phospho Tyr243) Rabbit Polyclonal Antibody, 100ul[BT-AP11860] DNA Libraries Synthesis Polymorphisms in this gene havePyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced

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Description

Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer

The alpha and beta tubulins represent the major components of microtubules

This protein preferentially induces apoptosis in transformed and tumor cells

which then phosphorylates and inactivates components of the apoptotic machinery

A related solute carrier family 11 protein gene is located on chromosome 2

PDHK1(Phospho Tyr243) Rabbit Polyclonal Antibody, 100ul[BT-AP11860] DNA Libraries Synthesis Polymorphisms in this gene havePyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced

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