CATB Rabbit Polyclonal Antibody, 20ul[BT-AP06919] Vacuum Aspirator TREML2 is located in a

TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086)

while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism

Association of this protein with the 4F complex is the rate-limiting step in translation initiation

This gene is also a candidate for several human lipodystrophy syndromes

The protein may function in the developing nervous system and play a role in tumorigenesis

CATB Rabbit Polyclonal Antibody, 20ul[BT-AP06919] Vacuum Aspirator TREML2 is located in aCatalytic activity: Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves Arg Arg Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase shows peptidyl dipeptidase activity liberating C terminal dipeptides. Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and