SP3 Polyclonal Antibody, 20ul Glassware Sets MARCH1 (membrane associated ring-CH-type finger

MARCH1 (membrane associated ring-CH-type finger 1) is a member of the MARCH family of membrane-bound E3 ubiquitin ligases

Multiple transcript variants for this gene exist

The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates| including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP

Tough and elastic with good impermeability

This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate| suggesting a role in repair of free-radical mediated DNA double-strand breaks

SP3 Polyclonal Antibody, 20ul Glassware Sets MARCH1 (membrane associated ring-CH-type fingerThis gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC and GT box regulatory elements in target genes. This protein contains a zinc finger DNA binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding