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TAF I p48 Polyclonal Antibody, 50ul Buffer Solutions This protein enhances the IL18-binding

SKU: 30362018265

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TAF I p48 Polyclonal Antibody, 50ul Buffer Solutions This protein enhances the IL18-bindingTAF1A (TATA box binding protein associated factor, RNA polymerase I subunit A) encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a TATA box binding protein associated factor that plays a role in the assembly of the RNA polymerase I preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple isoforms.

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Description

This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18

LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome

suggesting a role for CER in the pathology of these diseases

Deletion of TCF3 or diminished activity of the encoded protein may play a role in lymphoid malignancies

and a minor mediator of the JNK pathway

TAF I p48 Polyclonal Antibody, 50ul Buffer Solutions This protein enhances the IL18-bindingTAF1A (TATA box binding protein associated factor, RNA polymerase I subunit A) encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a TATA box binding protein associated factor that plays a role in the assembly of the RNA polymerase I preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple isoforms.

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