Human Interleukin-36 Alpha, IL1F6 ELISA Kit, 96T Deep Well Plates The protein encoded by this

The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family

This cluster includes several genes involved in regulation of the immune reaction

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at least one of which encodes a preproprotein that is proteolytically processed to generate the heavy chain of the inter-alpha-trypsin inhibitor complex

Several transcript variants encoding the same protein have been found for TNFAIP3

Human Interleukin-36 Alpha, IL1F6 ELISA Kit, 96T Deep Well Plates The protein encoded by thisCytokine that binds to and signals through the IL1RL2 IL 36R receptor which in turn activates NF kappa B and MAPK signaling pathways in target cells linked to a pro inflammatory response. Part of the IL 36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL 1 system with which it shares the coreceptor IL1RAP. Seems to be involved in skin inflammatory response by