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MMP-12 Polyclonal Antibody, 20ul[BT-AP05476] Buffer Solutions IGF-binding proteins prolong the half-life

SKU: 31276227477

4.4
PLN111.00 PLN151.00

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MMP-12 Polyclonal Antibody, 20ul[BT-AP05476] Buffer Solutions IGF-binding proteins prolong the half-lifeProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, Stromelysin 3 encoded by MMP11 is activated

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Description

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture

Additional variants are discussed in the literature

This protein enhances DNA binding and promotes processive DNA synthesis

The bone morphogenetic protein 15 encoded by BMP15 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily

DNA methylation

MMP-12 Polyclonal Antibody, 20ul[BT-AP05476] Buffer Solutions IGF-binding proteins prolong the half-lifeProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, Stromelysin 3 encoded by MMP11 is activated

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