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PKD1 Polyclonal Antibody, 100ul[BT-AP13117] Lysosome Mutations in this gene are

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PKD1 Polyclonal Antibody, 100ul[BT-AP13117] Lysosome Mutations in this gene arePRKD1 is a serine threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009

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Description

Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2

It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells

suggesting that these genes participate in blood cell-specific responses to interferons

Interacts with the PDZ domain of SHANK1

The protein encoded by this gene mediates calcium entry| and this entry is potentiated by calcium store depletion

PKD1 Polyclonal Antibody, 100ul[BT-AP13117] Lysosome Mutations in this gene arePRKD1 is a serine threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009

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