Rb(Phospho Ser795) Polyclonal Antibody, 100ul Cryogenic Vials and the counterbalancing phosphatase

and the counterbalancing phosphatase

CDH2 encodes a classical cadherin and member of the cadherin superfamily

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|PTM:Monomethylated| dimethylated or trimethylated at Lys-21

Mutations in this gene are associated with susceptibility to obesity in humans

Rb(Phospho Ser795) Polyclonal Antibody, 100ul Cryogenic Vials and the counterbalancing phosphataseThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.