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CAMLG Polyclonal Antibody, 100ul Palm Micro Centrifuges ASF1B (anti-silencing function 1B histone

SKU: 32554746286

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CAMLG Polyclonal Antibody, 100ul Palm Micro Centrifuges ASF1B (anti-silencing function 1B histoneThe immunosuppressant drug cyclosporin A blocks a calcium dependent signal from the T cell receptor (TCR) that normally leads to T cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This

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Description

ASF1B (anti-silencing function 1B histone chaperone) encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast

Metalloproteinase inhibitor 3 encoded by this gene family are inhibitors of the matrix metalloproteinases

The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis

Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups

DNA accessibility is regulated via a complex set of post-translational modifications of histones

CAMLG Polyclonal Antibody, 100ul Palm Micro Centrifuges ASF1B (anti-silencing function 1B histoneThe immunosuppressant drug cyclosporin A blocks a calcium dependent signal from the T cell receptor (TCR) that normally leads to T cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This

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