G Alpha i-3 Polyclonal Antibody, 50ul Cell Function Analysis Required for normal cytokinesis during

Required for normal cytokinesis during mitosis

Two transcript variants encoding distinct isoforms have been identified for this gene

RGS1 encodes a member of the regulator of G-protein signalling family

Binding to actin occurs through a C-terminal verprolin homology domain in all family members

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G Alpha i-3 Polyclonal Antibody, 50ul Cell Function Analysis Required for normal cytokinesis duringGuanine nucleotide binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. GNAI3 encodes an alpha subunit and belongs to the G alpha family. Mutation in this gene, resulting in a gly40 to arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein coupled endothelin receptor