PCSK9 Rabbit Polyclonal Antibody, 100ul[BT-AP11848] Hybridoma Antibody Sequencing SEPT5 is mapped to 22q11

SEPT5 is mapped to 22q11

Mutations in this gene have been associated with Pfeiffer syndrome

The encoded protein (solute carrier family 25 member 12) localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane

Expression of this gene is activated by the phosphatase and tensin homolog

and with CD3-gamma

PCSK9 Rabbit Polyclonal Antibody, 100ul[BT-AP11848] Hybridoma Antibody Sequencing SEPT5 is mapped to 22q11Proprotein convertase subtilisin kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1. It is the 9th member of the proprotein convertase family of proteins that activate other proteins. Similar genes (orthologs) are found across many species. As with many proteins, PCSK9 is inactive when first synthesized, because a section of peptide chains blocks their activity; proprotein convertases remove that section to activate