EDG-1(Phospho Thr236) Polyclonal Antibody, 20ul In vitro Assessment Mesencephalic astrocyte-derived neurotrophic factor encoded

Mesencephalic astrocyte-derived neurotrophic factor encoded by MANF is localized in the endoplasmic reticulum (ER) and golgi

Proteins expressed using the baculovirus-insect expression system retain full biological functionality and can accommodate larger exogenous fragments

The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid and submandibular/sublingual glands

a colorimetric substrate

This protein is involved in the elongation of long-chain polyunsaturated fatty acids

EDG-1(Phospho Thr236) Polyclonal Antibody, 20ul In vitro Assessment Mesencephalic astrocyte-derived neurotrophic factor encodedThe protein encoded by this gene is structurally similar to G protein coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine 1 phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell cell adhesion. Alternative splicing results in multiple transcript variants.