Shc(Phospho-Tyr317) Rabbit Polyclonal Antibody, 100ul Multiplex Immunoassays This gene is a member

This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X)

an important hormone and neurotransmitter

56kDa and 31kDa

The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature| suggesting that loss of the DAD1 protein triggered apoptosis

Some of these associations were further supported by gene expression analyses and an association study in essential hypersomnia (EHS)

Shc(Phospho-Tyr317) Rabbit Polyclonal Antibody, 100ul Multiplex Immunoassays This gene is a memberThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms p52Shc and p46Shc link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike