TNR8 Polyclonal Antibody, 20ul Cell Culture Flasks Tumor necrosis factor ligand superfamily

Tumor necrosis factor ligand superfamily member 10 encoded by TNFSF10 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family

The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor

Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported

it has been suggested that STK36 is a target for the treatment of these cancers

This gene encodes a protein that interacts with the low density lipoprotein (LDL) receptor-related protein and facilitates its proper folding and localization by preventing the binding of ligands

TNR8 Polyclonal Antibody, 20ul Cell Culture Flasks Tumor necrosis factor ligand superfamilyThe protein encoded by this gene is a member of the TNF receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body