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AKAP6 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Promotes constitutive and exonic splicing

SKU: 34894225049

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AKAP6 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Promotes constitutive and exonic splicingThe A kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and

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Description

Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins

This gene encodes a member of the Rho family of small GTPases| which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades

Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines

along with actin microfilaments and microtubules

It is thought to mediate calcineurin inhibition

AKAP6 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Promotes constitutive and exonic splicingThe A kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and

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