CREB-2(Phospho Ser219) Polyclonal Antibody, 50ul Endonucleases & Exonucleases it is packaged into neurosecretory

it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis

subcellular location:Associated with postsynaptic endosomes in hippocampal neurons

A related pseudogene is located on chromosome 9

The protein encoded by PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis

This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1

CREB-2(Phospho Ser219) Polyclonal Antibody, 50ul Endonucleases & Exonucleases it is packaged into neurosecretoryThis gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax responsive enhancer element in the LTR of HTLV 1. The encoded protein was also isolated and characterized as the cAMP response element binding protein 2 (CREB 2). The protein encoded by this gene belongs to a family of DNA binding proteins that includes the AP 1 family of transcription factors, cAMP response