F111A Rabbit Polyclonal Antibody, 50ul Bacterial Expression Defects in this gene are

Defects in this gene are associated with cell proliferation in certain cancers

Among its related pathways are Signaling by GPCR and Infectious disease

Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified

The long non-coding RNA transcripts interact with a variety of proteins

GBA3 is a polymorphic pseudogene

F111A Rabbit Polyclonal Antibody, 50ul Bacterial Expression Defects in this gene areThe protein encoded by this gene is cell cycle regulated and has nuclear localization. The C terminal half of the protein shares homology with trypsin like peptidases and it contains a PCNA interacting peptide (PIP) box that is necessary for its co localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects consistent with the demonstrated role for this gene in Simian Virus 40 (SV40)