Human Natural Resistance-associated Macrophage Protein 1, NRAMP-1 ELISA Kit , 96T Nucleic Acid Amplification Interacts with REL

Interacts with REL

This gene is located in an intron of the FBXL13 gene on the opposite strand

[Isoform 4]: Attenuates the ability of transcription factor HIF1A and EPAS1/HIF2A to bind to hypoxia-responsive elements (HRE) located within the enhancer/promoter of hypoxia-inducible target genes and hence inhibits HRE-driven transcriptional activation (PubMed: 16126907

increasing the rate of migration and cell-cell contacts in an integrin-dependent manner

integral membrane proteins that mediate calcium-dependent cell-cell adhesion

Human Natural Resistance-associated Macrophage Protein 1, NRAMP-1 ELISA Kit , 96T Nucleic Acid Amplification Interacts with RELDivalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own