IL-4R alpha(Phospho Tyr497) Polyclonal Antibody, 100ul Human Genome Knockout Libraries PYPAF or Cryopyrin

PYPAF or Cryopyrin

CEP135 (centrosomal protein 135) encodes a centrosomal protein

The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta)

and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200)

and a particular variation in this gene has been associated with obesity and insulin resistance in children

IL-4R alpha(Phospho Tyr497) Polyclonal Antibody, 100ul Human Genome Knockout Libraries PYPAF or CryopyrinThis gene encodes the alpha chain of the interleukin 4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane bound protein, and this soluble form can inhibit IL4 mediated cell proliferation and IL5 upregulation by T