Rat Bone Morphogenetic Protein 2, BMP-2 ELISA Kit , 96T Cellular Cultivation & Health Management |PTM:Ubiquitin-mediated proteolysis by SMAD-specific E3

|PTM:Ubiquitin-mediated proteolysis by SMAD-specific E3 ubiquitin ligase SMURF1

Maintains myogenic progenitors pool by suppressing differentiation through down-regulation of MYOD1 and is required for satellite cell homing and PAX7 expression (PubMed: 22940113)

May enhance HIF1A function by sequestering HIF1AN away from HIF1A

Involved in initiation and maintenance of cell cycle exit during cell differentiation

Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels

Rat Bone Morphogenetic Protein 2, BMP-2 ELISA Kit , 96T Cellular Cultivation & Health Management |PTM:Ubiquitin-mediated proteolysis by SMAD-specific E3Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3 EIF2A ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.