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DB125 Rabbit Polyclonal Antibody, 50ul Mini dry bath Members of this superfamily are

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DB125 Rabbit Polyclonal Antibody, 50ul Mini dry bath Members of this superfamily areDefensins are cysteine rich cationic polypeptides that are important in the host immunologic response to invading microorganisms. The antimicrobial protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome with this gene mapping to a cluster at 20p13.

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Description

Members of this superfamily are characterized by a signature 7-transmembrane domain motif

Plays an important role in signal transduction

The protein encoded by this gene is a regulatory protein involved in mitosis

was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages

The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4

DB125 Rabbit Polyclonal Antibody, 50ul Mini dry bath Members of this superfamily areDefensins are cysteine rich cationic polypeptides that are important in the host immunologic response to invading microorganisms. The antimicrobial protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome with this gene mapping to a cluster at 20p13.

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