ALKB3 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging This gene is imprinted and

This gene is imprinted and paternally expressed in lymphocytes but is more stochastically expressed in the placenta

This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis

Pseudogenes corresponding to this gene are found on chromosomes 2p

a disorder characterized by mental retardation

Mutations in this gene cause cryptogenic cirrhosis

ALKB3 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging This gene is imprinted andThe Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1 methyladenine and 3 methylcytosine (Duncan et al., 2002