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GR Polyclonal Antibody, 100ul[BT-AP03790] Antibodies Expression of this protein also

SKU: 39633546110

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GR Polyclonal Antibody, 100ul[BT-AP03790] Antibodies Expression of this protein alsoNR3C1 encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and

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Description

Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis

including ankyrin-like repeats

The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus

The encoded proteins also lack a C-terminus RING finger domain

Allelic variants are associated with prostate and brain cancer susceptibility

GR Polyclonal Antibody, 100ul[BT-AP03790] Antibodies Expression of this protein alsoNR3C1 encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and

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