Dsg2 Polyclonal Antibody, 100ul DNA Synthesis Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include nucleic acid binding and transcription factor activity

Allelic variants of this gene are associated with microcephaly

cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs)

Induction by IFN-gamma is enhanced by TNF-alpha in monocytes| dermal fibroblasts and endothelial cells| and by IL-1 in astrocytes

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Dsg2 Polyclonal Antibody, 100ul DNA Synthesis Gene Ontology (GO) annotations relatedDSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium binding transmembrane glycoprotein components of desmosomes, cell cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG2 is present in a gene cluster with other desmoglein gene family members on chromosome 18.