Bcl-x Polyclonal Antibody, 50ul[BT-AP00875] Cell Culture Flasks Mutations in this gene have

Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1)

Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis

Has lower activity with Lys-11 and Lys-33-linked ubiquitin chains

tissue specificity:Low level in normal B and T-cells

Despite the gene family name similarity

Bcl-x Polyclonal Antibody, 50ul[BT-AP00875] Cell Culture Flasks Mutations in this gene haveThe protein encoded by BCL2L1 (BCL2 like 1) belongs to the BCL 2 protein family. BCL 2 family members form hetero or homodimers and act as anti or pro apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and