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TGF beta 1 Polyclonal Antibody, 20ul[BT-AP14912] Miscellaneous Two of the isoforms (A

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4.1
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TGF beta 1 Polyclonal Antibody, 20ul[BT-AP14912] Miscellaneous Two of the isoforms (AThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature

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Description

Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap

It plays an important role in neuronal development and function

This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C| 1

Alternative coreceptor with CD4 for HIV-1 infection

Catalytic activity:Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone

TGF beta 1 Polyclonal Antibody, 20ul[BT-AP14912] Miscellaneous Two of the isoforms (AThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature

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