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Neu(Phospho Tyr1248) Polyclonal Antibody, 50ul Plates & Dishes Deletion of this gene sometimes

SKU: 4096216905

4.6
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Neu(Phospho Tyr1248) Polyclonal Antibody, 50ul Plates & Dishes Deletion of this gene sometimesThis gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those involving mitogen activated

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Description

Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype

It is thought to have an important role in signal transduction| cell proliferation and differentiation

BCCIP (BRCA2 and CDKN1A interacting protein) product was isolated on the basis of its interaction with BRCA2 and p21 proteins

The complex consists of the main channel-forming subunit alpha-1

Easy to disassemble and clean for periodic maintenance

Neu(Phospho Tyr1248) Polyclonal Antibody, 50ul Plates & Dishes Deletion of this gene sometimesThis gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those involving mitogen activated

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