IL-2R Beta Polyclonal Antibody, 100ul[BT-AP04491] Centrifuge Tube (Bottle) T-box transcription factor TBX3 is

T-box transcription factor TBX3 is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb

Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine

This gene encodes a member of the GIT protein family| which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity

Attenuates TNF-mediated endothelial expression of leukocyte adhesion molecules

Alternatively spliced transcript variants encoding different isoforms have been reported

IL-2R Beta Polyclonal Antibody, 100ul[BT-AP04491] Centrifuge Tube (Bottle) T-box transcription factor TBX3 isThe interleukin 2 receptor, which is involved in T cell mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha beta subunit heterodimer, while the high affinity form consists of an alpha beta gamma subunit heterotrimer. Both the intermediate and high affinity