N4BP1 Polyclonal Antibody, 100ul Stepper The type I isozyme has

The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities

A variant in this gene was associated with osteoarthritis

Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma

The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily

Nucleotide sugars| which are synthesized in the cytosol or the nucleus| are high-energy donor substrates for glycosyltransferases located in the lumen of the endoplasmic reticulum and Golgi apparatus

N4BP1 Polyclonal Antibody, 100ul Stepper The type I isozyme hasN4BP1 is a Protein Coding gene. NEDD4 Binding Protein 1 is a inhibitor of the E3 ubiquitin protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCHs substrates and impairing ubiquitination of substrates. Gene Ontology (GO) annotations related to this gene include RNA binding. An important paralog of this gene is ZC3H12C.