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Synuclein-alpha(Phospho Tyr125) Polyclonal Antibody, 50ul Cellular Function Assays a bipartite nuclear targeting signal

SKU: 4252799376

4.2
SEK185.00 SEK233.00

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Synuclein-alpha(Phospho Tyr125) Polyclonal Antibody, 50ul Cellular Function Assays a bipartite nuclear targeting signalAlpha synuclein is a member of the synuclein family, which also includes beta and gamma synuclein. Synucleins are abundantly expressed in the brain and alpha and beta synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with

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Description

a bipartite nuclear targeting signal

which may play a role in the response to environmental stress

MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al

This gene and the related gene biglycan are thought to be the result of a gene duplication

It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic

Synuclein-alpha(Phospho Tyr125) Polyclonal Antibody, 50ul Cellular Function Assays a bipartite nuclear targeting signalAlpha synuclein is a member of the synuclein family, which also includes beta and gamma synuclein. Synucleins are abundantly expressed in the brain and alpha and beta synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with

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