Phospho-BLM (T99) Polyclonal Antibody, 100ul DNA Oligo Synthesis The C1 domain does not

The C1 domain does not bind the diacylglycerol (DAG)

a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs

Expression in glioblastomas is highly variable

Does not interact with cAMP

This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily

Phospho-BLM (T99) Polyclonal Antibody, 100ul DNA Oligo Synthesis The C1 domain does notThe Bloom syndrome gene product is related to the RecQ subset of DExH box containing DNA helicases and has both DNA stimulated ATPase and ATP dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3' 5' helicase activity. The normal protein may act to suppress inappropriate recombination.