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Mnk1 Polyclonal Antibody, 20ul[BT-AP05494] sgRNA customized design The protein encodes a transcription

SKU: 4378599077

4.3
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Mnk1 Polyclonal Antibody, 20ul[BT-AP05494] sgRNA customized design The protein encodes a transcriptionMKNK1 (MAP kinase interacting serine threonine kinase 1) encodes a Ser Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C terminal region of eIF4G. Alternatively spliced transcript variants have been noted for MKNK1.

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Description

The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity

It can mediate both cell proliferation and p53-dependent/independent apoptosis

CMTM6 is widely expressed in many tissues

GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I

but may also be involved in the development of atherosclerosis

Mnk1 Polyclonal Antibody, 20ul[BT-AP05494] sgRNA customized design The protein encodes a transcriptionMKNK1 (MAP kinase interacting serine threonine kinase 1) encodes a Ser Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C terminal region of eIF4G. Alternatively spliced transcript variants have been noted for MKNK1.

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