MICU1 Monoclonal Antibody(Mix), 50ul Pathway and Network Analysis Studies suggest certain mutations in

Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE)

PTM:Binds keratan sulfate chains

and putative pseudogenes for this gene on chromosomes 2

This protein may have important functions in the extracellular matrix

Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress

MICU1 Monoclonal Antibody(Mix), 50ul Pathway and Network Analysis Studies suggest certain mutations inThis gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.