FLRT1 Polyclonal Antibody, 50ul Liquid Handling ＆Storage This gene encodes a subunit

This gene encodes a subunit of the splicing factor 3a protein complex

This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 10332

The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities

These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein

The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 55-78 copies in cases of SCA12

FLRT1 Polyclonal Antibody, 50ul Liquid Handling ＆Storage This gene encodes a subunitThis gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and or receptor signalling. Their protein structures resemble small leucine rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain.