IGF-IR Polyclonal Antibody, 50ul[BT-AP04396] Culture Media results in multiple transcripts encoding

results in multiple transcripts encoding different isoforms

In vitro assays indicate the protein lacks phosphorylation activity

This receptor belongs to the G-protein coupled receptor 1 family

A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis| catalyzing the decarboxylation of cysteinesulfinate to hypotaurine

Members of the subfamily share similarity in sequence and splice sites

IGF-IR Polyclonal Antibody, 50ul[BT-AP04396] Culture Media results in multiple transcripts encodingInsulin like growth factor 1 receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding